In this report we estimate the quantity of gas and the gas pressure resulting from a nuclear explosion in oil shale. These estimates are based on the thermal history of the rock during and after the explosion and the amount of gas that oil shale releases when heated. We estimate that for oil shale containing less than a few percent of kerogen the gas pressure will be lower than the hydrostatic pressure. A field program to determine the effects of nuclear explosions in rocks that simulate the unique features of oil shale is recommended.