In this report we present a preliminary assessment of the potential for CO2 disposal by sequestration in geological settings in Nevada using analysis with geographic information systems (GIS). The key assumptions made are that for CO2 disposal in saline aquifers it is wisest to (1) avoid underground disposal in areas of fractured bedrock and restrict the assessment to parts of alluvial basins that are thick enough to provide a seal against leakage and have sufficient pressure to keep the CO2 in a condensed phase; (2) stay away from active faults whose fracture zones may allow leakage of CO2 from underground injection sites; (3) avoid areas that in the foreseeable future have a reasonably high probability of being explored and developed for mineral, geothermal, or water resources; (4) avoid current urban areas and areas that are likely to experience significant population growth during the 21st century; and (5) avoid restricted lands, such as parks and military reservations. The data sets used in the GIS analysis are made available in the electronic version of this report, so that others may reevaluate the approach with different assumptions and data sets.