The Blake Ridge, off the southeastern United States, is marked by a large topography depression that is located directly on the ridge crest. The depression is considered to be a collapsed structure that appears to have been formed by gas hydrate-related processes. The mobilization of sediments that was required to produce this collapse probably would have triggered landslides if it took place on a steeper continental slope/rise, so the study of its formation will provide insight regarding the influence of gas hydrate on seafloor instabilities. The large sediment volume-loss associated with formation of the collapse probably transferred a large volume of methane from the sedimentary reservoir to the atmosphere and the process has probably influence the global greenhouse. This paper will consider the structure, causes, relationship to gas hydrate processes, and implications of this feature.